Skip to content
Free planNo credit card requiredStart writing
AI for Research home
AI for Research home
Dashboard
Sign inGet started

article · Russian Journal of Genetics · 2010

Expanding genetic code: Amino acids 21 and 22, selenocysteine and pyrrolysine

N. P. Lukashenko

Cited by 17Abstract and details only

Abstract

The discovery of two nonstandard amino acids, selenocysteine and pyrrolysine, in the genetic code is discussed. These findings have expanded our understanding of the genetic code, since the repertoire of amino acids in the genetic code was supplemented by two novel ones, in addition of the standard 20 amino acids. Current views on specific mechanisms of selenocysteine insertion in forming selenoproteins are considered, as well as the results of studies of new translational components involved in biosynthesis and incorporation of selenocysteine at different stages of translation. Similarity in the strategies of decoding UGA and UAG as codons for respectively selenocysteine and pyrrolysine is discussed. The review also presents evidence on the medical and biological role of selenium and selenoproteins containing selenocysteine as the main biological form of selenium.

Cite this paper

APA 7

Lukashenko, N. P. (2010). Expanding genetic code: Amino acids 21 and 22, selenocysteine and pyrrolysine. Russian Journal of Genetics, 46(8), 899–916. https://doi.org/10.1134/s1022795410080016

MLA 9

Lukashenko, N. P. “Expanding genetic code: Amino acids 21 and 22, selenocysteine and pyrrolysine.” Russian Journal of Genetics, vol. 46, no. 8, 2010, pp. 899–916, https://doi.org/10.1134/s1022795410080016.

Chicago

Lukashenko, N. P. 2010. “Expanding genetic code: Amino acids 21 and 22, selenocysteine and pyrrolysine.” Russian Journal of Genetics 46 (8): 899–916. https://doi.org/10.1134/s1022795410080016.

Harvard

Lukashenko, N.P. (2010) ‘Expanding genetic code: Amino acids 21 and 22, selenocysteine and pyrrolysine’, Russian Journal of Genetics, 46(8), pp. 899–916. Available at: https://doi.org/10.1134/s1022795410080016.

BibTeX
@article{lukashenko2010expanding,
  title = {{Expanding genetic code: Amino acids 21 and 22, selenocysteine and pyrrolysine}},
  author = {Lukashenko, N. P.},
  journal = {Russian Journal of Genetics},
  volume = {46},
  number = {8},
  pages = {899--916},
  year = {2010},
  doi = {10.1134/s1022795410080016}
}

Made from the index record. Check names, capitalisation and page numbers against the paper. Need another style? AI for Research has over 10,000.

Related papers