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article · Cold Spring Harbor Symposia on Quantitative Biology · 1967

Heterogeneity of Rabbit Light-Polypeptide Chains

R A Reisfeld

Cited by 10Abstract and details only

Abstract

Information concerning the heterogeneity of immunoglobulins, both as antigens and as antibodies, has been rapidly accumulating during the past years as has been discussed in detail in a number of recent reviews (Cohen and Porter, 1964; Nisonoff and Thorbecke, 1964; Fleischman, 1966). The electrophoretic heterogeneity of light polypeptide chains has been particularly well studied and described by many investigators. An example of a genetic control of heterogeneity of such molecules was provided by the discovery of allotypes (Oudin, 1956), the genetically controlled, antigenic forms of serum protein which differ among individuals within a species. We have carried out studies in order to understand the relationship between the genetic control of allotypic specificities and the structure and biosynthesis of rabbit γG-immunoglobins. We found chemical differences associated with allotypic specificities of light chains, such as distinct differences in amino acid composition and peptide maps, as well as a large degree of electrophoretic

Cite this paper

APA 7

Reisfeld, R. A. (1967). Heterogeneity of Rabbit Light-Polypeptide Chains. Cold Spring Harbor Symposia on Quantitative Biology, 32(0), 291–298. https://doi.org/10.1101/sqb.1967.032.01.041

MLA 9

Reisfeld, R A. “Heterogeneity of Rabbit Light-Polypeptide Chains.” Cold Spring Harbor Symposia on Quantitative Biology, vol. 32, no. 0, 1967, pp. 291–98, https://doi.org/10.1101/sqb.1967.032.01.041.

Chicago

Reisfeld, R A. 1967. “Heterogeneity of Rabbit Light-Polypeptide Chains.” Cold Spring Harbor Symposia on Quantitative Biology 32 (0): 291–98. https://doi.org/10.1101/sqb.1967.032.01.041.

Harvard

Reisfeld, R.A. (1967) ‘Heterogeneity of Rabbit Light-Polypeptide Chains’, Cold Spring Harbor Symposia on Quantitative Biology, 32(0), pp. 291–298. Available at: https://doi.org/10.1101/sqb.1967.032.01.041.

BibTeX
@article{reisfeld1967heterogeneity,
  title = {{Heterogeneity of Rabbit Light-Polypeptide Chains}},
  author = {Reisfeld, R A},
  journal = {Cold Spring Harbor Symposia on Quantitative Biology},
  volume = {32},
  number = {0},
  pages = {291--298},
  year = {1967},
  doi = {10.1101/sqb.1967.032.01.041}
}

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