Skip to content
Free planNo credit card requiredStart writing
AI for Research home
AI for Research home
Dashboard
Sign inGet started

review · Current Pharmaceutical Design · 2002

The Promise of Structural Genomics in the Discovery of New Antimicrobial Agents

Sean G. Buchanan, J.M. Sauder, Tess Harris

Cited by 12Abstract and details only

Abstract

Structural Genomics stands out among the emerging fields of proteomics since it influences the drug discovery process at so many points. Recent developments in protein expression technologies, x-ray crystallography and NMR spectroscopy provide the essential elements for high-throughput structure determination platforms. Bioinformatics methods to interrogate the resulting data will provide comprehensive, genome-wide databases of protein structure. Genomic sequencing and methods for high-throughput expression and protein purification are furthest advanced for microbial genes and so these have been the early targets for structural genomics initiatives. The information will be invaluable in understanding gene function, designing broad-spectrum small molecule inhibitors and in better understanding drug-host interactions.

Cite this paper

APA 7

Buchanan, S. G., Sauder, J., & Harris, T. (2002). The Promise of Structural Genomics in the Discovery of New Antimicrobial Agents. Current Pharmaceutical Design, 8(13), 1173–1188. https://doi.org/10.2174/1381612023394809

MLA 9

Buchanan, Sean G., et al. “The Promise of Structural Genomics in the Discovery of New Antimicrobial Agents.” Current Pharmaceutical Design, vol. 8, no. 13, 2002, pp. 1173–88, https://doi.org/10.2174/1381612023394809.

Chicago

Buchanan, Sean G., J.M. Sauder, and Tess Harris. 2002. “The Promise of Structural Genomics in the Discovery of New Antimicrobial Agents.” Current Pharmaceutical Design 8 (13): 1173–88. https://doi.org/10.2174/1381612023394809.

Harvard

Buchanan, S.G., Sauder, J. and Harris, T. (2002) ‘The Promise of Structural Genomics in the Discovery of New Antimicrobial Agents’, Current Pharmaceutical Design, 8(13), pp. 1173–1188. Available at: https://doi.org/10.2174/1381612023394809.

BibTeX
@article{buchanan2002promise,
  title = {{The Promise of Structural Genomics in the Discovery of New Antimicrobial Agents}},
  author = {Buchanan, Sean G. and Sauder, J.M. and Harris, Tess},
  journal = {Current Pharmaceutical Design},
  volume = {8},
  number = {13},
  pages = {1173--1188},
  year = {2002},
  doi = {10.2174/1381612023394809}
}

Made from the index record. Check names, capitalisation and page numbers against the paper. Need another style? AI for Research has over 10,000.

Related papers