book chapter · ASME Press eBooks · 2011

Tag SNP Selection Using Clonal Selection Algorithm Based on Support Vector Machine

İlhan İlhan, Yunus Emre Göktepe, Cengiz Özcan, Şirzat Kahramanlı

Cited by 4Abstract and details only

Abstract

Investigations on genetic variants associated with complex diseases are important for enhancements in diagnosis and treatments. SNPs (Single Nucleotide Polymorphisms), which comprise most of the millions of changes in human genome, are promising tools for disease-gene association studies. On the other hand, these studies are limited by cost of genotyping tremendous number of SNPs. Therefore, it is essential to identify a subset of SNPs that represents rest of the SNPs. As subset of SNPs is identified, data set should be searched as well as possible. In this study, a new method called CLONTagger was introduced, where Support Vector Machine (SVM) was used as SNP prediction method, whereas Clonal Selection Algorithm (CLONALG) was used as tag SNP selection method. The suggested method was compared with current tag SNP selection algorithms in literature using different datasets. Experimental results demonstrated that the suggested method could identify tag SNPs with better prediction accuracy than other methods from literature.

Cite this paper

APA 7

İlhan, İ., Göktepe, Y. E., Özcan, C., & Kahramanlı, Ş. (2011). Tag SNP Selection Using Clonal Selection Algorithm Based on Support Vector Machine. ASME Press eBooks, 47–57. https://doi.org/10.1115/1.859711.paper8

MLA 9

İlhan, İlhan, et al. “Tag SNP Selection Using Clonal Selection Algorithm Based on Support Vector Machine.” ASME Press eBooks, 2011, pp. 47–57, https://doi.org/10.1115/1.859711.paper8.

Chicago

İlhan, İlhan, Yunus Emre Göktepe, Cengiz Özcan, and Şirzat Kahramanlı. 2011. “Tag SNP Selection Using Clonal Selection Algorithm Based on Support Vector Machine.” ASME Press eBooks: 47–57. https://doi.org/10.1115/1.859711.paper8.

Harvard

İlhan, İ. et al. (2011) ‘Tag SNP Selection Using Clonal Selection Algorithm Based on Support Vector Machine’, ASME Press eBooks, pp. 47–57. Available at: https://doi.org/10.1115/1.859711.paper8.

BibTeX

@incollection{ilhan2011selection,
  title = {{Tag SNP Selection Using Clonal Selection Algorithm Based on Support Vector Machine}},
  author = {İlhan, İlhan and Göktepe, Yunus Emre and Özcan, Cengiz and Kahramanlı, Şirzat},
  booktitle = {ASME Press eBooks},
  pages = {47--57},
  year = {2011},
  doi = {10.1115/1.859711.paper8}
}

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