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article · Frontiers in Neuroscience · 2021

Quantitative Electroencephalogram Standardization: A Sex- and Age-Differentiated Normative Database

Juhee Ko, Ukeob Park, Daekeun Kim, Seung Wan Kang

Cited by 31Open access

Abstract

We describe the utility of a standardized index (Z-score) in quantitative EEG (QEEG) capable of when referenced to a resting-state, sex- and age-differentiated QEEG normative database (ISB-NormDB). Our ISB-NormDB comprises data for 1,289 subjects (553 males, 736 females) ages 4.5 to 81 years that met strict normative data criteria. A de-noising process allowed stratification based on QEEG variability between normal healthy men and women at various age ranges. The ISB-NormDB data set that is stratified by sex provides a unique, highly accurate ISB-NormDB model (ISB-NormDB: ISB-NormDB-Male, ISB-NormDB-Female). To evaluate the trends and accuracy of the ISB-NormDB, we used actual data to compare Z-scores obtained through the ISB-NormDB with those obtained through a traditional QEEG normative database to confirm that basic trends are maintained in most bands and are sensitive to abnormal test data. Finally, we demonstrate the value of our standardized index of QEEG, and highlight it's capacity to minimize the confounding variables of sex and age in any analysis.

Cite this paper

APA 7

Ko, J., Park, U., Kim, D., & Kang, S. W. (2021). Quantitative Electroencephalogram Standardization: A Sex- and Age-Differentiated Normative Database. Frontiers in Neuroscience, 15, 766781. https://doi.org/10.3389/fnins.2021.766781

MLA 9

Ko, Juhee, et al. “Quantitative Electroencephalogram Standardization: A Sex- and Age-Differentiated Normative Database.” Frontiers in Neuroscience, vol. 15, 2021, p. 766781, https://doi.org/10.3389/fnins.2021.766781.

Chicago

Ko, Juhee, Ukeob Park, Daekeun Kim, and Seung Wan Kang. 2021. “Quantitative Electroencephalogram Standardization: A Sex- and Age-Differentiated Normative Database.” Frontiers in Neuroscience 15: 766781. https://doi.org/10.3389/fnins.2021.766781.

Harvard

Ko, J. et al. (2021) ‘Quantitative Electroencephalogram Standardization: A Sex- and Age-Differentiated Normative Database’, Frontiers in Neuroscience, 15, p. 766781. Available at: https://doi.org/10.3389/fnins.2021.766781.

BibTeX
@article{ko2021quantitative,
  title = {{Quantitative Electroencephalogram Standardization: A Sex- and Age-Differentiated Normative Database}},
  author = {Ko, Juhee and Park, Ukeob and Kim, Daekeun and Kang, Seung Wan},
  journal = {Frontiers in Neuroscience},
  volume = {15},
  pages = {766781},
  year = {2021},
  doi = {10.3389/fnins.2021.766781}
}

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