article · Microorganisms · 2023
Non-Sterile Gloves as a Source of Radiation-Tolerant Microorganisms
Celine Cabeau, Romain Bolle-Reddat, James Hauschild, Gerald McDonnell
Cited by 2Open access
Abstract
Radiation methods are widely used for disinfection and sterilization applications. Microorganisms demonstrate known, variable tolerance levels to inactivation with lower doses of ionizing and non-ionizing radiation based on multiple mechanisms of resistance in their structures and nucleic acid repair mechanisms. The radiation dose required to ensure microbial inactivation during sterilization is typically based on the understanding and routine monitoring of the natural population and resistance of microorganisms on products exposed to radiation sterilization processes. This report describes the isolation of <i>Roseomonas mucosa</i> in a device manufacturing environment that was detected during routine device bioburden and dose verification monitoring. Sources of Gram-negative bacteria in the environment were investigated. Non-sterile examination gloves used during manufacturing were found to be a persistent source of <i>R. mucosa</i> and other microbial contaminants. The source of contamination was determined to be from the glove manufacturing process. Maintenance and routine microbiological controls during glove manufacturing, including water systems, are required to reduce the risks of gloves being a source of unexpected microbiological contamination.
Cite this paper
Cabeau, C., Bolle-Reddat, R., Hauschild, J., & McDonnell, G. (2023). Non-Sterile Gloves as a Source of Radiation-Tolerant Microorganisms. Microorganisms, 11(12), 2859. https://doi.org/10.3390/microorganisms11122859
Cabeau, Celine, et al. “Non-Sterile Gloves as a Source of Radiation-Tolerant Microorganisms.” Microorganisms, vol. 11, no. 12, 2023, p. 2859, https://doi.org/10.3390/microorganisms11122859.
Cabeau, Celine, Romain Bolle-Reddat, James Hauschild, and Gerald McDonnell. 2023. “Non-Sterile Gloves as a Source of Radiation-Tolerant Microorganisms.” Microorganisms 11 (12): 2859. https://doi.org/10.3390/microorganisms11122859.
Cabeau, C. et al. (2023) ‘Non-Sterile Gloves as a Source of Radiation-Tolerant Microorganisms’, Microorganisms, 11(12), p. 2859. Available at: https://doi.org/10.3390/microorganisms11122859.
@article{cabeau2023sterile,
title = {{Non-Sterile Gloves as a Source of Radiation-Tolerant Microorganisms}},
author = {Cabeau, Celine and Bolle-Reddat, Romain and Hauschild, James and McDonnell, Gerald},
journal = {Microorganisms},
volume = {11},
number = {12},
pages = {2859},
year = {2023},
doi = {10.3390/microorganisms11122859}
}Made from the index record. Check names, capitalisation and page numbers against the paper. Need another style? AI for Research has over 10,000.