dataset · Figshare · 2016
A Scalable Addressable Positive-Dielectrophoretic\nCell-Sorting Array
Brian M. Taff (2459359), Joel Voldman (109682)
Cited by 0Open access
Abstract
We present the first known implementation of a passive,\nscalable architecture for trapping, imaging, and sorting\nindividual microparticles, including cells, using a positive\ndielectrophoretic (p-DEP) trapping array. Our array-based\ntechnology enables “active coverslips” where, when scaled,\nmany individually held cells can be sorted based upon\nimaged spatial or temporally variant characteristics. Our\ndesign incorporates a unique “ring-dot” p-DEP trap\ngeometry organized in a row/column array format. This\ntrap design, implemented in a two-level metal process,\nprovides strong and highly spatially localized holding\nfields enabling single-cell capture for all traps in the array.\nWe release individual trapped microparticles during sorting using a passive transistor-independent approach\nwhere we electrically ground the row and column electrodes associated with specific traps in the array. The\ndemand for chip-to-world electrical connections in our\narrays scales proportionally with the square root of the\nnumber of traps in a given array, delivering a substantial\nimprovement over prior designs. We demonstrate capture, holding, and release operations with both beads and\ncells in small arrays of this new architecture.
Cite this paper
(2459359), B. M. T., & (109682), J. V. (2016). A Scalable Addressable Positive-Dielectrophoretic\nCell-Sorting Array. Figshare. https://doi.org/10.1021/ac0513616.s002
(2459359), Brian M. Taff, and Joel Voldman (109682). “A Scalable Addressable Positive-Dielectrophoretic\nCell-Sorting Array.” Figshare, 2016, https://doi.org/10.1021/ac0513616.s002.
(2459359), Brian M. Taff, and Joel Voldman (109682). 2016. “A Scalable Addressable Positive-Dielectrophoretic\nCell-Sorting Array.” Figshare. https://doi.org/10.1021/ac0513616.s002.
(2459359), B.M.T. and (109682), J.V. (2016) ‘A Scalable Addressable Positive-Dielectrophoretic\nCell-Sorting Array’, Figshare. Available at: https://doi.org/10.1021/ac0513616.s002.
@misc{24593592016scalable,
title = {{A Scalable Addressable Positive-Dielectrophoretic\nCell-Sorting Array}},
author = {(2459359), Brian M. Taff and (109682), Joel Voldman},
journal = {Figshare},
year = {2016},
doi = {10.1021/ac0513616.s002}
}Made from the index record. Check names, capitalisation and page numbers against the paper. Need another style? AI for Research has over 10,000.