other · Figshare · 2023

Graphical model.

Florencia Sabbione (4862455), Irene Angelica Keitelman (17692572), Carolina Maiumi Shiromizu (11754866), Alexia Vereertbrugghen (11183433), Douglas Vera Aguilar (13418307), Paolo Nahuel Rubatto Birri (17692575), Manuela Pizzano (17692578), María Victoria Ramos (15473954), Federico Fuentes (149005), Lucas Saposnik (17692581), Agostina Cernutto (17692584), Juliana Cassataro (357586), Carolina Cristina Jancic (11754872), Jeremías Gaston Galletti (17692587), Marina Sandra Palermo (15473960), Analía Silvina Trevani (9458076)

Cited by 0Open access

Abstract

<p><b><a href="https://openclipart.org/detail/36289/scissors" target="_blank">https://openclipart.org/detail/36289/scissors</a></b>. Challenge of neutrophils with STEC induces ROS production dependent on NADPH oxidase activation. ROS would trigger elastase release from azurophil granules to the cytosol which could be able to process both Gasdermin D (GSDMD) and pro-IL-1β. Likewise, STEC also trigger inflammasome activation and consequently caspase-1 activation which is able to also process both GSDMD and pro-IL-1β. The N-terminal fragment of GSDMD can form pores on azurophil granule membranes increasing elastase leakage to the cytosol. The amount of active cytosolic elastase would determine if pro-IL-1β is processed to the mature IL-1β isoform or degraded.</p>

Cite this paper

APA 7

(4862455), F. S., (17692572), I. A. K., (11754866), C. M. S., (11183433), A. V., (13418307), D. V. A., (17692575), P. N. R. B., (17692578), M. P., (15473954), M. V. R., (149005), F. F., (17692581), L. S., (17692584), A. C., (357586), J. C., (11754872), C. C. J., (17692587), J. G. G., (15473960), M. S. P., & (9458076), A. S. T. (2023). Graphical model. Figshare. https://doi.org/10.1371/journal.ppat.1011877.g008

MLA 9

(4862455), Florencia Sabbione, et al. “Graphical model.” Figshare, 2023, https://doi.org/10.1371/journal.ppat.1011877.g008.

Chicago

(4862455), Florencia Sabbione, Irene Angelica Keitelman (17692572), Carolina Maiumi Shiromizu (11754866), Alexia Vereertbrugghen (11183433), Douglas Vera Aguilar (13418307), Paolo Nahuel Rubatto Birri (17692575), Manuela Pizzano (17692578), et al. 2023. “Graphical model.” Figshare. https://doi.org/10.1371/journal.ppat.1011877.g008.

Harvard

(4862455), F.S. et al. (2023) ‘Graphical model’, Figshare. Available at: https://doi.org/10.1371/journal.ppat.1011877.g008.

BibTeX

@misc{48624552023graphical,
  title = {{Graphical model.}},
  author = {(4862455), Florencia Sabbione and (17692572), Irene Angelica Keitelman and (11754866), Carolina Maiumi Shiromizu and (11183433), Alexia Vereertbrugghen and (13418307), Douglas Vera Aguilar and (17692575), Paolo Nahuel Rubatto Birri and (17692578), Manuela Pizzano and (15473954), María Victoria Ramos and (149005), Federico Fuentes and (17692581), Lucas Saposnik and (17692584), Agostina Cernutto and (357586), Juliana Cassataro and (11754872), Carolina Cristina Jancic and (17692587), Jeremías Gaston Galletti and (15473960), Marina Sandra Palermo and (9458076), Analía Silvina Trevani},
  journal = {Figshare},
  year = {2023},
  doi = {10.1371/journal.ppat.1011877.g008}
}

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