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article · Methods in molecular biology · 2013

Mutation and Mutation Screening

L. Slade Lee, Bradley J. Till, Helen Hill, Owen A. Huynh, Joanna Jankowicz-Cieślak

Cited by 20Abstract and details only

Abstract

Molecular techniques have created the opportunity for great advances in plant mutation genetics and the science of mutation breeding. The powerful targeted induced local lesions in genomes (TILLING) technique has introduced the possibility of reverse genetics—the ability to screen for mutations at the DNA level prior to assessing phenotype. Fundamental to TILLING is the induction of mutant populations (or alternatively, the identification of mutants in the environment); and mutation induction requires an understanding and assessment of the appropriate mutagen dose required. The techniques of mutation induction, dose optimization, and TILLING are explained.

Cite this paper

APA 7

Lee, L. S., Till, B. J., Hill, H., Huynh, O. A., & Jankowicz-Cieślak, J. (2013). Mutation and Mutation Screening. Methods in molecular biology, 77–95. https://doi.org/10.1007/978-1-62703-715-0_8

MLA 9

Lee, L. Slade, et al. “Mutation and Mutation Screening.” Methods in molecular biology, 2013, pp. 77–95, https://doi.org/10.1007/978-1-62703-715-0_8.

Chicago

Lee, L. Slade, Bradley J. Till, Helen Hill, Owen A. Huynh, and Joanna Jankowicz-Cieślak. 2013. “Mutation and Mutation Screening.” Methods in molecular biology: 77–95. https://doi.org/10.1007/978-1-62703-715-0_8.

Harvard

Lee, L.S. et al. (2013) ‘Mutation and Mutation Screening’, Methods in molecular biology, pp. 77–95. Available at: https://doi.org/10.1007/978-1-62703-715-0_8.

BibTeX
@article{lee2013mutation,
  title = {{Mutation and Mutation Screening}},
  author = {Lee, L. Slade and Till, Bradley J. and Hill, Helen and Huynh, Owen A. and Jankowicz-Cieślak, Joanna},
  journal = {Methods in molecular biology},
  pages = {77--95},
  year = {2013},
  doi = {10.1007/978-1-62703-715-0_8}
}

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