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About 10,000 papers for “Anesthesia”

Local Anesthesia and Conduction Anesthesia

Zulfiya Makhmudovna, Buzrukzoda Javohir · Zenodo (CERN European Organization for Nuclear Research) · 2026

This study is devoted to the characterization of popular local anesthetics and the determination of the mosteffective drugs for local anesthesia. The authors conducted a review of current scientific publications examining theproperties of local anesthetics, their pharmacokinetic and pharmacodynamic characteristics, as well as methods of application.The study was carried out in two directions: using traditional printed sources and online databases. The collecteddata allowed for a comparative analysis of the medications, taking into account their beneficial properties and potentialside effects. As a result of this analysis, the drug with the optimal balance of favorable characteristics was identified.During the research, key criteria determining the choice of the drug were identified: efficacy, duration of the latent period,duration of action, and level of toxicity. To perform local anesthesia during a surgical intervention, an anesthetic withhigh efficacy and a rapid onset of action (short latency time) is required. It is essential that the anesthetic provide a longlastinganalgesic effect, allowing for a single administration even during prolonged surgery while maintaining low toxicity.Seven local anesthetics were analyzed in the study: procaine (novocaine), lidocaine, tetracaine (dicaine), benzocaine(anesthesin), articaine, mepivacaine, and bupivacaine. Comparative data revealed certain disadvantages for each drug.Procaine (novocaine) is prone to causing allergic reactions, while lidocaine is characterized by a relatively short durationof action. The high toxicity of tetracaine (dicaine) makes it unsuitable for conduction, infiltration, and epidural anesthesia.Benzocaine (anesthesin), due to its low water solubility, is not suitable for parenteral administration. Articaine stands outamong local anesthetics due to its high potency-to-toxicity ratio, which accounts for its priority use in clinical practice asa local anesthetic.

Cited by 0Open access

Anesthesia 2050: A Better Anesthesia?

Thomas M. Hemmerling · Anesthesia & Analgesia · 2024

From the Division of Experimental Surgery, Department of Anesthesiology, McGill University, Montreal, Quebec, Canada. Funding: None. Accepted for publication October 6, 2023. Conflicts of Interest: See Disclosures at the end of the article. Address correspondence to Thomas M. Hemmerling, MSc, MD, DEAA, Department of Anesthesiology, McGill University, Montreal General Hospital, 1650 Cedar Ave, Travancore Bldg, T8-108, Montreal, Quebec H3G 1A4, Canada. Address e-mail to [email protected].

Cited by 3

Local Anesthesia and Conduction Anesthesia

Zulfiya Makhmudovna, Buzrukzoda Javohir · Zenodo (CERN European Organization for Nuclear Research) · 2026

This study is devoted to the characterization of popular local anesthetics and the determination of the mosteffective drugs for local anesthesia. The authors conducted a review of current scientific publications examining theproperties of local anesthetics, their pharmacokinetic and pharmacodynamic characteristics, as well as methods of application.The study was carried out in two directions: using traditional printed sources and online databases. The collecteddata allowed for a comparative analysis of the medications, taking into account their beneficial properties and potentialside effects. As a result of this analysis, the drug with the optimal balance of favorable characteristics was identified.During the research, key criteria determining the choice of the drug were identified: efficacy, duration of the latent period,duration of action, and level of toxicity. To perform local anesthesia during a surgical intervention, an anesthetic withhigh efficacy and a rapid onset of action (short latency time) is required. It is essential that the anesthetic provide a longlastinganalgesic effect, allowing for a single administration even during prolonged surgery while maintaining low toxicity.Seven local anesthetics were analyzed in the study: procaine (novocaine), lidocaine, tetracaine (dicaine), benzocaine(anesthesin), articaine, mepivacaine, and bupivacaine. Comparative data revealed certain disadvantages for each drug.Procaine (novocaine) is prone to causing allergic reactions, while lidocaine is characterized by a relatively short durationof action. The high toxicity of tetracaine (dicaine) makes it unsuitable for conduction, infiltration, and epidural anesthesia.Benzocaine (anesthesin), due to its low water solubility, is not suitable for parenteral administration. Articaine stands outamong local anesthetics due to its high potency-to-toxicity ratio, which accounts for its priority use in clinical practice asa local anesthetic.

Cited by 0Open access

Periodontal anesthesia and mandibular anesthesia

Emmerich, O. Borges · The Journal of the Abraham Lincoln Association

Editors: Aug. 1859-July 1865, J. D. White, J. H. McQuillen, G. J. Ziegler.--Aug. 1865-Dec. 1871, J. H. McQuillen, G. J. Ziegler.--Jan. 1872-May 1891, J. W. White.--July 1891-Apr. 1930, E. C. Kirk (with L. P. Anthony, Dec. 1917-Apr. 1930).--May 1930-Dec. 1936, L. P. Anthony.

Cited by 0

General Anesthesia Versus Regional Anesthesia

Patrick J. Breen, Kyung W. Park · International Anesthesiology Clinics · 2002

No distinct advantage is apparent between regional and general anesthesia when considering perioperative cardiac morbidity and mortality in peripheral vascular surgery. However, there is some evidence to support regional anesthesia over general anesthesia in an effort to optimize graft patency if the regional technique is extended into the postoperative period to provide neuraxial analgesia. An inadequate number of randomized, controlled trials have been conducted to determine whether regional or general anesthesia should be performed for carotid endarterectomy. The nonrandomized trials do support regional anesthesia by virtue of reductions in stroke, myocardial infarction, and death. A randomized, prospective trial is needed to verify these outcomes. The choice of technique does not appear to affect mortality in patients requiring hip fracture surgery, although Urwin et al. (29) reported less 1-month mortality in patients receiving regional anesthesia. General anesthesia has been associated with increased blood loss and thromboembolic complications in patients undergoing hip fracture repair. Epidural anesthesia has been shown to promote quicker return of bowel function postoperatively when the catheter has been sited at T12 or higher. Anastomotic breakdown in patients with epidural anesthesia/analgesia has rarely been reported. Most studies tend to show quicker return of bowel function when local anesthetics alone are administered epidurally.

Cited by 61

165. Anesthesia 101: Local Anesthesia

Surgery 101 · Internet Archive (Internet Archive) · 2015

This week Anesthesia Resident Urooj Siddiqui talks about Local Anesthesia. After listening to the podcast learners will be able to: Describe the pharmacology of local anesthetics Look at the different types of local anesthetics Highlight the different techniques used in local anesthesia Outline the toxicities associated with common local anesthetic agents Recognize the indications for and against the use of local anesthetics

Cited by 0

Anesthesia

Jensen, Amber · Open PRAIRIE (South Dakota State University) · 2019

Cited by 0Open access

Anesthesia,

Gwathmey, James Tayloe, 1862-1944., Baskerville, Charles, 1870-1922. · The Journal of the Abraham Lincoln Association

Cited by 0Open access

anesthesia

Jean de Dieu MAHORO · Open MIND · 2026

data set

Cited by 0Open access

anesthesia

Jean de Dieu MAHORO · Open MIND · 2026

data set

Cited by 0Open access

Anesthesia

Knox, Gordon, Elwyn, Robert, Gray, Hugh et al. · University of North Texas Digital Library (University of North Texas)

"This film has been prepared as an aid to the physician in obtaining a more complete understanding of the procedures, the limitations, and the advantages of Vinethene anesthesia" - from film.

Cited by 0