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Cell Type

Dermatopathology · 2011

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CELL TYPE‐DEPENDENT COLLAGEN‐TYPE RECOGNITION BY CELL RECEPTORS

L. A. Sadofiev, Н. С. Николаенко, Natalia Kalmykova et al. · Cell Biology International · 2001

Affinity chromatography of a number of cell types on collagens I and III reveals three proteins with M(R)of 250, 170 and 140 kDa. These proteins are able to discriminate between types I and III, but not types III and IV. Collagen-type recognition is therefore characteristic for cells of connective tissue origin. Polyclonal antibodies (Ab) raised against 170 and 140 kDa polypeptides and used in immunofluorescence show membrane localisation for both, with their distribution being similar to each other and to the distribution of the integrin beta1 chain. Ab p140 and commercial monoclonal antibodies against alpha(2)chain stain a band of the same molecular mass as from purified collagen binding proteins from liver cells, indicating that the 140 kDa protein is probably the alpha(2)integrin chain. The alpha(2)chain containing integrins are therefore able to discriminate collagen types I and III and collagen type recognition by this receptor is cell-type dependent.

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Cell Type names

Daniel Bunis · Figshare · 2022

Names for the 64 cell types in xCell signature for Fig.3.

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Cell Type names

Bunis, Daniel · Figshare · 2022

Names for the 64 cell types in xCell signature for Fig.3.

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GO Cell Type

Modabbernia, Amirhossein · Figshare · 2021

Robustness of the GO findings to selecting genes related to a specific cell-type

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Cell type clustering.

Samuel P. Ingram (9854133), Nicholas T. Henthorn (9854136), John W. Warmenhoven (9854139) et al. · Figshare · 2020

<p>Interactive 3D plot of the total DSB clustering for a range of cluster radii and LET for the three cell types: IMR90, GM12878 and HMEC.</p> <p>(HTML)</p>

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Cell type biomarkers.

Anna Papiez (6166616), Jonathan Pioch (18880345), Hans-Joachim Mollenkopf (157038) et al. · Figshare · 2024

<p>Cell type biomarker genes used to identify 15 human immune cell subtypes.</p> <p>(XLSX)</p>

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Cell Type Explorer

Koskela, Sanna, Burnett, Laura, Dreher, Marisa et al. · Zenodo (CERN European Organization for Nuclear Research) · 2025

Cell Type Explorer, a supplement to "Connectome-driven neural inventory of a complete visual system" (Nern et al., 2025; https://doi.org/10.1038/s41586-025-08746-0). Browse the Cell Type Explorer at https://reiserlab.github.io/male-drosophila-visual-system-connectome/ or download the long-term archived version from here. Abstract from the manuscript: Vision provides animals with detailed information about their surroundings, conveying diverse features such as color, form, and movement across the visual scene. Computing these parallel spatial features requires a large and diverse network of neurons, such that in animals as distant as flies and humans, visual regions comprise half the brain’s volume. These visual brain regions often reveal remarkable structure-function relationships, with neurons organized along spatial maps with shapes that directly relate to their roles in visual processing. To unravel the stunning diversity of a complex visual system, a careful mapping of the neural architecture matched to tools for targeted exploration of that circuitry is essential. Here, we report a new connectome of the right optic lobe from a male Drosophila central nervous system FIB-SEM volume and a comprehensive inventory of the fly’s visual neurons. We developed a computational framework to quantify the anatomy of visual neurons, establishing a basis for interpreting how their shapes relate to spatial vision. By integrating this analysis with connectivity information, neurotransmitter identity, and expert curation, we classified the ∼53,000 neurons into 727 types, about half of which are systematically described and named for the first time. Finally, we share an extensive collection of split-GAL4 lines matched to our neuron type catalog. Together, this comprehensive set of tools and data unlock new possibilities for systematic investigations of vision in Drosophila, a foundation for a deeper understanding of sensory processing. The Cell Type Explorer is a set of static webpages with information about the cell types from the preprint.

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Cell Type Explorer

Koskela, Sanna, Burnett, Laura, Dreher, Marisa et al. · Zenodo (CERN European Organization for Nuclear Research) · 2025

Cell Type Explorer, a supplement to "Connectome-driven neural inventory of a complete visual system" (Nern et al., 2025; https://doi.org/10.1038/s41586-025-08746-0). Browse the Cell Type Explorer at https://reiserlab.github.io/male-drosophila-visual-system-connectome/ or download the long-term archived version from here. Abstract from the manuscript: Vision provides animals with detailed information about their surroundings, conveying diverse features such as color, form, and movement across the visual scene. Computing these parallel spatial features requires a large and diverse network of neurons, such that in animals as distant as flies and humans, visual regions comprise half the brain’s volume. These visual brain regions often reveal remarkable structure-function relationships, with neurons organized along spatial maps with shapes that directly relate to their roles in visual processing. To unravel the stunning diversity of a complex visual system, a careful mapping of the neural architecture matched to tools for targeted exploration of that circuitry is essential. Here, we report a new connectome of the right optic lobe from a male Drosophila central nervous system FIB-SEM volume and a comprehensive inventory of the fly’s visual neurons. We developed a computational framework to quantify the anatomy of visual neurons, establishing a basis for interpreting how their shapes relate to spatial vision. By integrating this analysis with connectivity information, neurotransmitter identity, and expert curation, we classified the ∼53,000 neurons into 727 types, about half of which are systematically described and named for the first time. Finally, we share an extensive collection of split-GAL4 lines matched to our neuron type catalog. Together, this comprehensive set of tools and data unlock new possibilities for systematic investigations of vision in Drosophila, a foundation for a deeper understanding of sensory processing. The Cell Type Explorer is a set of static webpages with information about the cell types from the preprint.

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Cell type table.

Asa Farahani (21807894), Zhen-Qi Liu (21807897), Eric G. Ceballos (21807900) et al. · Figshare · 2025

<div> Blood perfusion delivers oxygen and nutrients to all cells, making it a fundamental feature of brain organization. How cerebral blood perfusion maps onto micro-, meso- and macro-scale brain structure and function is therefore a key question in neuroscience. Here we analyze pseudo-continuous arterial spin labeling (ASL) data from 1305 healthy individuals in the HCP Lifespan studies (5–22 and 36–100 years) to reconstruct a high-resolution normative cerebral blood perfusion map. At the cellular and molecular level, cerebral blood perfusion co-localizes with granular layer IV, biological pathways for maintenance of cellular relaxation potential and mitochondrial organization, and with neurotransmitter and neuropeptide receptors involved in vasomodulation. At the regional level, blood perfusion aligns with cortical arealization and is greatest in regions with high metabolic demand and resting-state functional hubs. Looking across individuals, blood perfusion is dynamic throughout the lifespan, follows micro-architectural changes in development, and maps onto individual differences in physiological changes in aging. In addition, we find that cortical atrophy in multiple neurodegenerative diseases (late-onset Alzheimer’s disease, TDP-43C, and dementia with Lewy bodies) is most pronounced in regions with lower perfusion, highlighting the utility of perfusion topography as an indicator of transdiagnostic vulnerability. Finally, we show that ASL-derived perfusion can be used to delineate arterial territories in a data-driven manner, providing insights into how the vascular system is linked to human brain function. Collectively, this work highlights how cerebral blood perfusion is central to, and interlinked with, multiple structural and functional systems in the brain. </div>

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Cell type identification.

Junjie Sun (4383520), Jiaying Qiu (4959496), Qiongxia Yang (13762759) et al. · Figshare · 2022

&lt;p&gt;(A) The average expression of each marker gene in different cell types; the darker the red, the higher the expression. (B) UMAP visualization shows the expression of marker genes in different cell types; the darker the red, the higher the expression.&lt;/p&gt; &lt;p&gt;(TIF)&lt;/p&gt;

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GO Cell Type

Modabbernia, Amirhossein · Figshare · 2021

Robustness of the GO findings to selecting genes related to a specific cell-type

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cell-type-specific

Sharon L. Squazzo, Vitalina M. Komashko, Sheryl R. Krig et al. · 2006

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Cell Type Code

National Cancer Institute · Definitions · 2020

Ope n Pe

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Cell type identification.

Junjie Sun (4383520), Jiaying Qiu (4959496), Qiongxia Yang (13762759) et al. · Figshare · 2022

&lt;p&gt;(A) UMAP visualization showing the cluster of cell type from scRNA-seq. (B) The heatmap shows the average expression of marker genes for each cell type. The darker the yellow, the higher the expression level. (C) The proportion of each cell type to the total number of cells. (D) UMAP visualization showing the distribution of SMA and control cells. (E) Proportion of cells from SMA or control samples in each cell type.&lt;/p&gt;

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Cell type annotations

Lapohos, Orsolya · Figshare · 2024

Cell type annotations used in the corresponding manuscript.

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Cell Type Identified

Hematopoietic Progenitors, Hla-dr L Igga, Iggcd Ico · 2015

Human HLA-DR/CD34: sc-3942 is a direct immunofluorescence reagent formatted to identify and determine the percentage of myeloid progenitor cells in erythrocyte-lysed whole blood, based on cell-surface antigen expression. HLA-DR is a class II MHC antigen that is expressed on B lymphocytes, monocytes, macrophages, activated T lymphocytes, activated NK lymphocytes and on human hematopoietic progenitor cells (1-3). HLA-DR is also present on thymic epithelium, B-lymphocyte-dependent areas of spleen and lymph node and B-cell lymphomas (4). CD34 is a marker for myeloid progenitor cells (5). CD34 expression is highest on early hematopoietic progenitor cells, decreases as cells mature and is absent on fully differentiated hematopoietic cells (6). ISOTYPE CONTROL sc-3942 CON (IgG2a FITC/IgG1 PE) is the isotype matched negative control for this system and is suitable for 50 tests.

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Cell Type Testing

Bas Kokshoorn · 2023

Body fluids may be informative for the reconstruction of criminal events. Blood on the clothing of suspects may for instance link them to a complainant having been hit over the head. Whether the substance recovered is blood and whether this material is from the suspect or somebody else are the issues that are discussed in this chapter. The concepts of the interpretation of body fluids and human tissue testing are discussed. We conclude that confirmatory tests do not exist but that, given specific task-relevant case information, a conclusion may be reached that a sample contains a particular body fluid. Examples of probabilistic assessment of cell type testing results to address source-level issues are shown. As it may be considered that cell type testing is only relevant to address activity-level issues, the chapter concludes with the exploration of the use of cell type testing results in an example case.

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Cell type annotations

Lapohos, Orsolya · Figshare · 2024

Cell type annotations used in the corresponding manuscript.

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Myoepithelial Carcinoma Spindle cell type, Clear cell type, and Plasmacytoid type: Serial Kasus A Case Series of Myoepithelial Carcinoma Spindle cell type, Clear cell type, and Plasmacytoid type

Dian Yuliartha Lestari, Dyah Fauziah · Bulletin of Miscellaneous Information (Royal Gardens Kew) · 2018

Myoepithelial Carcinoma adalah salah satu keganasan kelenjar liur yang sangat jarang terjadi, dimana terdiri dari komponen sel-sel myoepithelial yang berdifferensiasi sebagai sel spindle, sel jernih (clear), sel epitheloid, sel stelate, maupun sel plasmacytoid. Kami melaporkan 3 kasus myoepithelial carcinoma yang didiagnosis di Rumah Sakit Dr. Soetomo Surabaya dalam kurun waktu 4 tahun terakhir dengan ti ga tipe yang berbeda, yaitu; spindle cell type, clear cell type, dan plasmacytoid type. Dua kasus terjadi pada kelenjar parotis, lainnya pada kelenjar submandibula, dimana ketiganya terjadi pada wanita dengan rentang usia 45-76 tahun. Keluhan saat datang berobat adalah timbul benjolan semakin membesar secara perlahan dan tidak menimbulkan nyeri. Hasil pemeriksaan histopatologis menyatakan suatu carcinoma mengesankan myoepithelial carcinoma. Hasil pemeriksaan immunohistokimia smooth muscle actin (SMA)dan S100 mayoritas menunjukkan hasil yang positif, dimana menyokong diagnosis suatu myoepithelial carcinoma

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