There is clear evidence that parents can and do influence children. There is equally clear evidence that children’s genetic makeup affects their own behavioral characteristics, and also influences the way they are treated by their parents. Twin and ...Read More

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Life-Span Development

Tian Yuan · 2023

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Life Span Ethics

Ph.D. Carla D. Sanderson · DigitalGeorgetown (Georgetown University Library) · 2013

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Life Span Ethics

Carla D. Sanderson, Ph.D. · DigitalGeorgetown (Georgetown University Library) · 2013

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Platelet Life Span

Frank H. Gardner, Phin Cohen · Transfusion · 1966

In the past decade platelet transfusions into thrombocytopenic recipients indicated that the platelet had a curvilinear lifespan. These early studies showed that platelet transfusions could be used to demonstrate shortened lifespans of platelets in idiopathic acute and chronic thrombocytopenic purpura. In addition, progressive shortening of the platelet lifespan followed the administration of multiple transfusions. A variety of isotopes has been used to gather further information regarding platelet physiology in the non‐thrombocytopenic recipient. For the most part, irregular labeling or re‐utilization of the isotope has made these procedures unsatisfactory except for sodium chromate (Cr 51 ). Modification of ACD anticoagulant has been helpful in eliminating the initial sequestration of platelets noted earlier with EDTA anticoagulant. These more precise measurements have confirmed the linear, senescent, lifespan of the human blood platelet. A comparison of platelet measurements in the recipient by numerical counting and radioactivity of platelets has indicated that the data may not be comparable. These differences may be related to in vivo elution of the Cr 51 label. For complete understanding of the platelet lifespan investigators should confirm isotope data with numerical counting of platelets.

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Life-Span Development

2015

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Life-Span Extension

Christian Sell, Antonello Lorenzini, Holly M. Brown‐Borg et al. · Humana Press eBooks · 2009

In recent years, remarkable discoveries have been made concerning the underlying mechanisms of aging. In Life-Span Extension: Single-Cell Organisms to Man, the editors bring together a range of illuminating perspectives from researchers investigating the aging process in a variety of species. This novel work addresses the aging process in species ranging from yeast to man and, among other subjects, features detailed discussions of the naked mole-rat, an exceptionally long-lived rodent; the relationship between dietary factors/food restriction and aging; and an evolutionary view of the human aging process. Single mutations that extend life span have been identified in yeast, worms, flies, and mice, whereas studies in humans have identified potentially important markers for successful aging. At the same time, it has been discovered that the genes and pathways identified in these studies involve a surprisingly small set of conserved functions, most of which have been the focus of aging research for some time. For example, the mTOR pathway, a regulator of translation and protein synthesis, has been identified as a common longevity pathway in yeast and Caenorhabditis elegans. In mammals, this pathway intersects with neuroendocrine pathways and with the insulin/insulin-like growth factor pathways, which have been identified as major modulators of life span and aging in both invertebrates and mice. Novel, emerging technologies and the increasingly wide variety of systems that are now used to study aging and the mechanisms of aging provide enormous opportunities for the identification of common pathways that modulate longevity. It is these common pathways that are the focus of this important volume.

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Life-Span Communication

Patterson, Brian R. · The Research Repository @ WVU (West Virginia University) · 2017

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Life span measurements.

Laetitia Chauve (8600553), Francesca Hodge (11632178), Sharlene Murdoch (6306368) et al. · Figshare · 2021

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Life Span Development

Fenwick W.English · Encyclopedia of Educational Leadership and Administration · 2006

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Life Span: Overview

Lani V. Jones · Encyclopedia of Social Work · 2013

This entry provides an overview of the life-span perspective focusing on biological developments and social tasks all of which are embedded in a larger sociocultural context from birth to old age within diverse environments, cultures, and historical eras. This section will also focus on how the life-span perspective succeeds traditional life course models that assume to be universal, sequential, and predictable. The life-span perspective of social work departs from approaches based on traditional models that are narrow and focuses on personal deficits, pointing instead to strengths, continued growth, and environmental resources for individuals, families, groups, and communities. Finally, this entry will discuss how the life-span perspective shows great promise for encompassing theory of human development for the purpose of expanding knowledge, promoting “best practice” service delivery, policy regulation and research to enhance the lives of people with whom social workers come into contact.

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Life Span of

2016

doi:10.1093/gerona/gls070 1 BY delaying or reducing the onset of multiple late-life diseases, treatments that increase longevity could have a far greater benefit to quality of life than treatments targeted at single late-life diseases such as cancer or heart disease (1–3). There are numerous reports of dietary additives pur-ported to have beneficial effects in rodent models (4–6), but until recently none have been replicated and accepted by the scientific community as a reliable and reproducible result. In 2003, the National Institute on Aging established the NIA Interventions Testing Program (ITP) to evaluate agents that are hypothesized to delay aging in laboratory mice and thus prevent or delay multiple diseases of late life. The central features of the ITP protocol have been described elsewhere (7–11). Briefly, test agents are nominated by

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Life-Span Development

Susanne Wurm, Anna E. Kornadt · 2021

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Life-Span Process

2021

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