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Microsphere

Abdus Samad, Mohammad Tariq, Mohammed Rabiul Alam et al. · Surfactant science · 2010

Cited by 3

MicroSphere

Bulletin of Miscellaneous Information (Royal Gardens Kew) · 2007

Cited by 0

microsphere

Riccardo De Pascalis, I. David Abrahams, William J. Parnell · 2015

Cited by 0

Microsphere

Eli Breuer, Mukund S. Chorghade, János Fischer et al. · IUPAC Standards Online · 2016

This Glossary of Terms Related to Pharmaceutics is needed by practitioners in the field of pharmaceutics as this field fulfills an important and crucial role, different from the roles of other scientific disciplines involved in the drugmaking process. The glossary contains 168 definitions used in pharmaceutics. These are related to various aspects of this discipline, such as: (1) physicochemical characterization of pharmaceutical preparations and the active ingredients they contain; (2) unit operations used in the practice of pharmaceutics; (3) terms related to the various dosage forms; (4) terms related to the various modes and routes of drug delivery; (5) terms used in pharmacokinetics and biopharmaceutics in general; and additional miscellaneous terms. The field of pharmaceutics itself is of a multidisciplinary nature as its practitioners come from a variety of disciplines, such as chemistry or various biological sciences, thus a glossary containing authoritative definitions would be useful for them. The terms used in pharmaceutics are rarely covered by existing glossaries, and in the cases they are, their definitions are often inappropriate for the field of pharmaceutics and require new or modified definitions to better fit the new context.

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Microsphere array

The Dictionary of Genomics, Transcriptomics and Proteomics · 2015

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Polymer Microsphere

Stanisław Słomkowski, José Alemán, Robert G. Gilbert et al. · IUPAC Standards Online · 2016

A large group of industrially important polymerization processes is carried out in dispersed systems. These processes differ with respect to their physical nature, mechanism of particle formation, particle morphology, size, charge, types of interparticle interactions, and many other aspects. Polymer dispersions, and polymers derived from polymerization in dispersed systems, are used in diverse areas such as paints, adhesives, microelectronics, medicine, cosmetics, biotechnology, and others. Frequently, the same names are used for different processes and products or different names are used for the same processes and products. The document contains a list of recommended terms and definitions necessary for the unambiguous description of processes, products, parameters, and characteristic features relevant to polymers in dispersed systems.

Cited by 0Open access

Proteinoid Microsphere

Koichiro Matsuno · Encyclopedia of Astrobiology · 2023

Cited by 1

Proteinoid Microsphere

Koichiro Matsuno · Encyclopedia of Astrobiology · 2011

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Reproducing Microsphere

Koichiro MATSUNO · Seibutsu Butsuri · 1983

Molecular aggregates or molecular automata that could appear during chemical and protobiological evolution have boundary conditions of their own. The preceding products during molecular synthesis keep providing the boundary conditions for the subsequent production process. The successive feedback from product to production and the resulting internalization of the boundary conditions are the main mechanism underlying the evolution of functional molecular aggregates. The internalization of the boundary conditions and their endogenous changes with time are identified in the experimental protobiogenesis of thermal polymerization of amino acids, microsphere formation from the resulting thermal proteins and the reproduction of these microspheres. The physical process responsible for the internalization of the boundary conditions is material flow equilibration of an open material aggregate. Material flow equilibration is a process by which an open material aggregate constantly and endogenously changes its interaction with its exterior so as to maintain the continuity of material flow there. Both variations and constraints applied to the evolution of material aggregates are due to material flow equilibration and thus are inseparable. Protobiological information originates in the physical process by which the boundary conditions for molecular aggregates are formed endogenously.

Cited by 0Open access

microsphere, n.

Oxford University Press eBooks · 2023

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Microsphere Overview

Shiv Kumar Sah, Mrs. Vasia, Rajkumar Prasad Yadav et al. · Asian Journal of Pharmaceutical Research and Development · 2021

The aim of developing continuous or managed delivery mechanisms has always been to minimise dosage duration, resulting in improved patient compliance and less side effects. Microspheres have been shown to minimise dosage, side effects, administration frequency, and the risk of dose dumping. As a result, patient compliance has improved.Targeted drug delivery mechanisms aim for a specific location in the body to maximise drug concentration in a specific tissue or organ, thus improving the drug's therapeutic effectiveness. Microspheres have promised targeted or managed drug distribution in the body for decades, and have shown to be superior to traditional drug delivery. The goal of this review different aspects of the microparticulate drug delivery system along with types of microspheres and methods of preparation and different applications as targeted or controlled drug delivery system.

Cited by 1Open access

Microsphere Study

K. Kore Bhushan Dhoran* · Zenodo (CERN European Organization for Nuclear Research) · 2026

Microspheres are solid, spherical drug delivery systems with particle sizes ranging from 1 to 1000 µm. They improve therapeutic efficacy by delivering controlled and targeted release. They are made from natural or synthetic polymers and can encapsulate pharmaceuticals in a polymeric matrix or a unique coating. Microspheres can assist reduce dose frequency, reduce side effects, and improve patient compliance. Depending on the physicochemical parameters of the drug and polymer, many preparation procedures are used, including single emulsion, double emulsion, solvent evaporation, phase separation coacervation, and spray drying. Microspheres are categorized into several varieties, including bioadhesive, magnetic, floating, radioactive, and polymeric microspheres, each with a distinct therapeutic purpose. These methods made considerable use of chemotherapy, gene delivery, vaccination adjuvants, ocular delivery, and lymphatic targeting.

Cited by 0Open access

Microsphere Study

K. Kore Bhushan Dhoran* · Zenodo (CERN European Organization for Nuclear Research) · 2026

Microspheres are solid, spherical drug delivery systems with particle sizes ranging from 1 to 1000 µm. They improve therapeutic efficacy by delivering controlled and targeted release. They are made from natural or synthetic polymers and can encapsulate pharmaceuticals in a polymeric matrix or a unique coating. Microspheres can assist reduce dose frequency, reduce side effects, and improve patient compliance. Depending on the physicochemical parameters of the drug and polymer, many preparation procedures are used, including single emulsion, double emulsion, solvent evaporation, phase separation coacervation, and spray drying. Microspheres are categorized into several varieties, including bioadhesive, magnetic, floating, radioactive, and polymeric microspheres, each with a distinct therapeutic purpose. These methods made considerable use of chemotherapy, gene delivery, vaccination adjuvants, ocular delivery, and lymphatic targeting.

Cited by 0Open access

Microsphere characterization.

Laura Fernández-Sánchez (142885), Irene Bravo-Osuna (4047400), Pedro Lax (143830) et al. · Figshare · 2017

<p>(A) Scanning electron microscopy picture of TUDCA-loaded microspheres. Insets: particle size distribution. (B) Cumulative <i>in vitro</i> release of TUDCA (μg/mg MSs) over 28 days from TUDCA-loaded PLGA MSs in PBS (pH 7.4).</p>

Cited by 0Open access

Microsphere probe: combining microsphere-assisted microscopy with AFM

Yujian Hong, Shasha Xiao, Cong Zhai et al. · Optics Express · 2023

In recent years, microsphere-assisted microscopy (MAM) and atomic force microscope (AFM) have been rapidly developed to meet the measurement needs of microstructures. However, the positioning of microspheres, the inability of AFM to touch the underlying sample through the transparent insulating layer, and the challenge of AFM fast positioning limit their use in practical measurements. In this paper, we propose a method that combines MAM with AFM by adhering the microsphere to the cantilever. This method allows MAM and AFM to work in parallel, and their imaging positions can correspond with each other. We use this method to measure memory devices, and the results show that MAM and AFM yield complementary advantages. This approach provides a new tool for analyzing complex structures in devices and has potential for wide application.

Cited by 10Open access

Microsphere probe: Combining microsphere-assisted microscopy with AFM

Hong, Yujian, Xiao, Shasha, Zhai, Cong et al. · Figshare · 2023

In recent years, microsphere-assisted microscopy (MAM) and atomic force microscope (AFM) have been rapidly developed to meet the measurement needs of microstructures. However, the positioning of microspheres, the inability of AFM to touch the underlying sample through the transparent insulating layer, and the challenge of AFM fast positioning limit their use in practical measurements. In this paper, we propose a method that combines MAM with AFM by adhering the microsphere to the cantilever. This method allows MAM and AFM to work in parallel, and their imaging positions can correspond with each other. We use this method to measure memory devices, and the results show that MAM and AFM yield complementary advantages. This approach provides a new tool for analyzing complex structures in devices and has potential for wide application.

Cited by 0Open access

Microsphere probe: Combining microsphere-assisted microscopy with AFM

Hong, Yujian, Xiao, Shasha, Zhai, Cong et al. · Figshare · 2023

In recent years, microsphere-assisted microscopy (MAM) and atomic force microscope (AFM) have been rapidly developed to meet the measurement needs of microstructures. However, the positioning of microspheres, the inability of AFM to touch the underlying sample through the transparent insulating layer, and the challenge of AFM fast positioning limit their use in practical measurements. In this paper, we propose a method that combines MAM with AFM by adhering the microsphere to the cantilever. This method allows MAM and AFM to work in parallel, and their imaging positions can correspond with each other. We use this method to measure memory devices, and the results show that MAM and AFM yield complementary advantages. This approach provides a new tool for analyzing complex structures in devices and has potential for wide application.

Cited by 0Open access

Magnetic Microsphere and Method of Forming a Microsphere

Wen, Weijia, Sheng, Ping, Gong, Xiuqing et al. · Rare & Special e-Zone (The Hong Kong University of Science and Technology) · 2016

The microspheres have many possible applications including smart drug delivery, breaking and damper devices. In one arrangement, a microsphere comprises a shell 120 and a core 110. The core comprises a liquid, which may be a drug, while the shell comprises magnetic particles. The microsphere is deformable in response to application of an external magnetic field. Also disclose is an arrangement in which a microsphere has a magnetic core and a PDMS shell.

Cited by 0Open access

Microsphere probe: Combining microsphere-assisted microscopy with AFM

Hong, Yujian, Xiao, Shasha, Zhai, Cong et al. · Figshare · 2023

In recent years, microsphere-assisted microscopy (MAM) and atomic force microscope (AFM) have been rapidly developed to meet the measurement needs of microstructures. However, the positioning of microspheres, the inability of AFM to touch the underlying sample through the transparent insulating layer, and the challenge of AFM fast positioning limit their use in practical measurements. In this paper, we propose a method that combines MAM with AFM by adhering the microsphere to the cantilever. This method allows MAM and AFM to work in parallel, and their imaging positions can correspond with each other. We use this method to measure memory devices, and the results show that MAM and AFM yield complementary advantages. This approach provides a new tool for analyzing complex structures in devices and has potential for wide application.

Cited by 0Open access

Flexible Microsphere-Embedded Film for Microsphere-Enhanced Raman Spectroscopy

Xing Cheng, Yinzhou Yan, Chao Feng et al. · ACS Applied Materials & Interfaces · 2017

Dielectric microspheres with extraordinary microscale optical properties, such as photonic nanojets, optical whispering-gallery modes (WGMs), and directional antennas, have drawn interest in many research fields. Microsphere-enhanced Raman spectroscopy (MERS) is an alternative approach for enhanced Raman detection by dielectric microstructures. Unfortunately, fabrication of microsphere monolayer arrays is the major challenge of MERS for practical applications on various specimen surfaces. Here we report a microsphere-embedded film (MF) by immersing a highly refractive microsphere monolayer array in the poly(dimethylsiloxane) (PDMS) film as a flexible MERS sensing platform for one- to three-dimensional (1D to 3D) specimen surfaces. The directional antennas and wave-guided whispering-gallery modes (WG-WGMs) contribute to the majority of Raman enhancement by the MFs. Moreover, the MF can be coupled with surface-enhanced Raman spectroscopy (SERS) to provide an extra >10-fold enhancement. The limit of detection is therefore improved for sensing of crystal violet (CV) and Sudan I molecules in aqueous solutions at concentrations down to 10^-7 M. A hybrid dual-layer microsphere enhancer, constructed by depositing a MF onto a microsphere monolayer array, is also demonstrated, wherein the WG-WGMs become dominant and boost the enhancement ratio >50-fold. The present work opens up new opportunities for design of cost-effective and flexible MERS sensing platforms as individual or associated techniques toward practical applications in ultrasensitive Raman detection.

Cited by 46