Xiao‐Jing Wang · Oxford University Press eBooks · 2010
The prefrontal cortex is a vital cortical substrate for higher brain functions and flexible control of behavior. The functional versatility of the prefrontal cortex owns in part to its extensive input–output connections with the rest of the brain. Sufficiently strong and slow recurrent synaptic connections endow the prefrontal circuits with the ability to maintain self-sustained persistent neural activity underlying working memory, and to carry out slow time integration of information during decision-making. Excitation is balanced by inhibition mediated by several types of inhibitory interneurons, which display a different distribution in the prefrontal cortex from early sensory areas and which are important for such processes as filtering out distracting stimuli, generating competition in selective attention, or choosing among response alternatives. Therefore, whereas the prefrontal cortex may share a similar layout as other cortical areas, quantitative differences in their microcircuit properties give rise to qualitatively different functions of critical importance to cognition.
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Tetsuya Iidaka, Tokiko Harada, Norihiro Sadato · 2016
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John P Christianson, Benjamin N Greenwood, See Profile et al. · 2013
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Fp Battaglia, A Peyrache, M Khamassi et al. · 2014
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National Cancer Institute · Definitions · 2020
Ope n Pe
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Susan Y. Bookheimer · 2021
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Deepak Ν. Pandya, Benjamin Seltzer, Michael Petrides et al. · Cerebral Cortex · 2015
Abstract After a brief historical account of frontal lobe studies, the current architectonic parcellation of the frontal cortex is described in the context of the dual origin concept. Intrinsic and distant connections of the frontal cortical areas are also described according to this concept. The chapter goes on to touch upon the importance of the prefrontal cortex in decision-making, response to stimuli, motivation, emotion, and working memory and controlled memory retrieval. The usefulness of the dual origin concept for behavioral and neuroimaging studies is then discussed.
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Joaquı́n M. Fuster · Elsevier eBooks · 2001
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Joseph L. Price · 2006
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Richard E. Passingham · 2021
Abstract The key to the granular prefrontal (PF) cortex is that it sits at the top of the sensory processing hierarchy, the motor hierarchy, and the outcome hierarchy. This means that it is a position to learn abstract task rules. These relate to conditional tasks that involve sequences, associations, and attentional performance. Because they can learn abstract rules, primates can show specific behavioural transfer from one problem to another when the problems share the same logic. And, since the different PF areas are closely interconnected, the PF cortex provides a general-purpose mechanism for the rapid solution of novel tasks.
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Branislav Filipovic, Ana Starcevic · Directory of Open access Books (OAPEN Foundation) · 2018
The prefrontal cortex reaches its greatest development in the human brain, making up nearly one third of the neocortex. Due to its remarkable evolution, the prefrontal cortex plays an important role in higher integrative functions such as information processing, thinking, understanding, attention, behavior, motivation, emotions, working memory, and analysis. This book brings together theoretical and technical research advances on the prefrontal cortex, from the basic explanations of the neuronal architecture of the prefrontal cortex and its anatomy, presenting it as a morphological substrate for many psychological conditions, through normal and altered connectivity and its manifestation in different behavior and identification of organizational levels inside the prefrontal cortex through different neuroimaging methods. It also provides an interdisciplinary view of the prefrontal cortex and its issues and discovers the main role of this part of brain in psychosocial, economic, and cultural adaptation.
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Roger J. R. Levesque · 2018
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2006
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John P Christianson, Benjamin N Greenwood, See Profile et al. · 2013
All in-text\treferences\tunderlined\tin\tblue\tare\tlinked\tto\tpublications\ton\tResearchGate, letting you\taccess\tand\tread\tthem\timmediately.
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Nancy Oraham · Radiopaedia.org · 2026
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Matthew V. Chafee, Sarah R. Heilbronner · Current Biology · 2022
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Richard D. Kensinger · 2025
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Tetsuya Iidaka, Tokiko Harada, Norihiro Sadato · 2016
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Gretchen Schoenfield · 2011
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Ian P. Stolerman, Lawrence H. Price · 2015
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