Childhood leukaemia: a relationship between intracellular 6‐mercaptopurine metabolites and neutropenia
Lynne Lennard, Corinne Rees, J S Lilleyman et al. · British Journal of Clinical Pharmacology · 2004
Cited by 159Open access
Author · Alder Hey Children's NHS Foundation Trust
J L Maddocks
- Works
- 46
- Cited by
- 1,033
- h-index
- 17
Most-cited papers
Assay of 6-thioguanine nucleotide, a major metabolite of azathioprine, 6-mercaptopurine and 6-thioguanine, in human red blood cells
Lynne Lennard, John L. Maddocks · Journal of Pharmacy and Pharmacology · 1983
Cited by 112
Skin cancer in renal transplant recipients is associated with increased concentrations of 6-thioguanine nucleotide in red blood cells
Lynne Lennard, S. THOMAS, CHRISTINE I. HARRINGTON et al. · British Journal of Dermatology · 1985
Cited by 98
" INDIRECT PATHOGENICITY " OF PENICILLINASE-PRODUCING ENTEROBACTERIA IN CHRONIC BRONCHIAL INFECTIONS
John L. Maddocks, J. Robert May · The Lancet · 1969
Cited by 72
A rapid method for identifying bacterial enzymes.
John L. Maddocks, M J Greenan · Journal of Clinical Pathology · 1975
Cited by 59Open access
AZATHIOPRINE AND SEVERE BONE MARROW DEPRESSION
John L. Maddocks, Lynne Lennard, J. A. L. AMESS et al. · The Lancet · 1986
Cited by 56
Rational Design of Novel Immunosuppressive Drugs: Analogues of Azathioprine Lacking the 6-Mercaptopurine Substituent Retain or Have Enhanced Immunosuppressive Effects
Duncan J. K. Crawford, John L. Maddocks, David N. Jones et al. · Journal of Medicinal Chemistry · 1996
Cited by 52
6-Mercaptopurine: apparent lack of relation between prescribed dose and biological effect in children with leukaemia
S M Herber, Lynne Lennard, J S Lilleyman et al. · British Journal of Cancer · 1982
Cited by 43Open access
Blue rubber bleb naevus disease: an uncommon cause of gastrointestinal tract bleeding.
Marian C. Jennings, P Ward, John L. Maddocks · Gut · 1988
Cited by 35Open access
Childhood lymphoblastic leukaemia: Sex difference in 6-mercaptopurine utilization
J S Lilleyman, Lynne Lennard, Corinne Rees et al. · British Journal of Cancer · 1984
Cited by 35Open access
Transient hemiparetic attacks due to unrecognised nocturnal hypoglycaemia.
Joseph H. Silas, D S Grant, John L. Maddocks · BMJ · 1981
Cited by 34Open access
The effect of folate supplements on 6-mercaptopurine remission maintenance therapy in childhood leukaemia
Lynne Lennard, J S Lilleyman, John L. Maddocks · British Journal of Cancer · 1986
Cited by 33Open access
Headache Due to Ischaemic Heart Disease
Robert Fleetcroft, John L. Maddocks · Journal of the Royal Society of Medicine · 1985
Cited by 24Open access
2,8-dihydroxyadenine urolithiasis
H. Anne Simmonds, Karel J. Van Acker, Amrik S. Sahota et al. · The Lancet · 1992
Cited by 23
Toxic Epidermal Necrolysis, Agranulocytosis and Erythroid Hypoplasia associated with Sulphasalazine
John L. Maddocks, David N. Slater · Journal of the Royal Society of Medicine · 1980
Cited by 23Open access