article · Neural Regeneration Research · 2014

Mild hypothermia for treatment of diffuse axonal injury: a quantitative analysis of diffusion tensor imaging

Guojie Jing, Xiaoteng Yao, Yiyi Li, Yituan Xie, Wangan Li, Kejun Liu, Yingchao Jing, Baisheng Li, Yifan Lv, Baoxin Ma

Cited by 5Open access

Abstract

Fractional anisotropy values in diffusion tensor imaging can quantitatively reflect the consistency of nerve fibers after brain damage, where higher values generally indicate less damage to nerve fibers. Therefore, we hypothesized that diffusion tensor imaging could be used to evaluate the effect of mild hypothermia on diffuse axonal injury. A total of 102 patients with diffuse axonal injury were randomly divided into two groups: normothermic and mild hypothermic treatment groups. Patient's modified Rankin scale scores 2 months after mild hypothermia were significantly lower than those for the normothermia group. The difference in average fractional anisotropy value for each region of interest before and after mild hypothermia was 1.32-1.36 times higher than the value in the normothermia group. Quantitative assessment of diffusion tensor imaging indicates that mild hypothermia therapy may be beneficial for patients with diffuse axonal injury.

Cite this paper

APA 7

Jing, G., Yao, X., Li, Y., Xie, Y., Li, W., Liu, K., Jing, Y., Li, B., Lv, Y., & Ma, B. (2014). Mild hypothermia for treatment of diffuse axonal injury: a quantitative analysis of diffusion tensor imaging. Neural Regeneration Research, 9(2), 190. https://doi.org/10.4103/1673-5374.125348

MLA 9

Jing, Guojie, et al. “Mild hypothermia for treatment of diffuse axonal injury: a quantitative analysis of diffusion tensor imaging.” Neural Regeneration Research, vol. 9, no. 2, 2014, p. 190, https://doi.org/10.4103/1673-5374.125348.

Chicago

Jing, Guojie, Xiaoteng Yao, Yiyi Li, Yituan Xie, Wangan Li, Kejun Liu, Yingchao Jing, Baisheng Li, Yifan Lv, and Baoxin Ma. 2014. “Mild hypothermia for treatment of diffuse axonal injury: a quantitative analysis of diffusion tensor imaging.” Neural Regeneration Research 9 (2): 190. https://doi.org/10.4103/1673-5374.125348.

Harvard

Jing, G. et al. (2014) ‘Mild hypothermia for treatment of diffuse axonal injury: a quantitative analysis of diffusion tensor imaging’, Neural Regeneration Research, 9(2), p. 190. Available at: https://doi.org/10.4103/1673-5374.125348.

BibTeX

@article{jing2014mild,
  title = {{Mild hypothermia for treatment of diffuse axonal injury: a quantitative analysis of diffusion tensor imaging}},
  author = {Jing, Guojie and Yao, Xiaoteng and Li, Yiyi and Xie, Yituan and Li, Wangan and Liu, Kejun and Jing, Yingchao and Li, Baisheng and Lv, Yifan and Ma, Baoxin},
  journal = {Neural Regeneration Research},
  volume = {9},
  number = {2},
  pages = {190},
  year = {2014},
  doi = {10.4103/1673-5374.125348}
}

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