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article · Methods in molecular biology · 2009

Machine Learning: An Indispensable Tool in Bioinformatics

Iñaki Inza, Borja Calvo, Rubén Armañanzas, Endika Bengoetxea, Pedro Larrañaga, José A. Lozano

Cited by 99Abstract and details only

Abstract

The increase in the number and complexity of biological databases has raised the need for modern and powerful data analysis tools and techniques. In order to fulfill these requirements, the machine learning discipline has become an everyday tool in bio-laboratories. The use of machine learning techniques has been extended to a wide spectrum of bioinformatics applications. It is broadly used to investigate the underlying mechanisms and interactions between biological molecules in many diseases, and it is an essential tool in any biomarker discovery process. In this chapter, we provide a basic taxonomy of machine learning algorithms, and the characteristics of main data preprocessing, supervised classification, and clustering techniques are shown. Feature selection, classifier evaluation, and two supervised classification topics that have a deep impact on current bioinformatics are presented. We make the interested reader aware of a set of popular web resources, open source software tools, and benchmarking data repositories that are frequently used by the machine learning community.

Cite this paper

APA 7

Inza, I., Calvo, B., Armañanzas, R., Bengoetxea, E., Larrañaga, P., & Lozano, J. A. (2009). Machine Learning: An Indispensable Tool in Bioinformatics. Methods in molecular biology, 593, 25–48. https://doi.org/10.1007/978-1-60327-194-3_2

MLA 9

Inza, Iñaki, et al. “Machine Learning: An Indispensable Tool in Bioinformatics.” Methods in molecular biology, vol. 593, 2009, pp. 25–48, https://doi.org/10.1007/978-1-60327-194-3_2.

Chicago

Inza, Iñaki, Borja Calvo, Rubén Armañanzas, Endika Bengoetxea, Pedro Larrañaga, and José A. Lozano. 2009. “Machine Learning: An Indispensable Tool in Bioinformatics.” Methods in molecular biology 593: 25–48. https://doi.org/10.1007/978-1-60327-194-3_2.

Harvard

Inza, I. et al. (2009) ‘Machine Learning: An Indispensable Tool in Bioinformatics’, Methods in molecular biology, 593, pp. 25–48. Available at: https://doi.org/10.1007/978-1-60327-194-3_2.

BibTeX
@article{inza2009machine,
  title = {{Machine Learning: An Indispensable Tool in Bioinformatics}},
  author = {Inza, Iñaki and Calvo, Borja and Armañanzas, Rubén and Bengoetxea, Endika and Larrañaga, Pedro and Lozano, José A.},
  journal = {Methods in molecular biology},
  volume = {593},
  pages = {25--48},
  year = {2009},
  doi = {10.1007/978-1-60327-194-3_2}
}

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